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NEA HEALTH INFORMATION NETWORK

Getting
Involved with Medical Research

Advances in
medicine and science are the results of new ideas and approaches
developed through research. Clinical trials (also called medical
research and research studies) are used to determine whether new
drugs or treatments are both safe and effective. A clinical trial
is a research study to answer specific questions about vaccines
or new therapies or new ways of using known treatments. Carefully
conducted clinical trials are the fastest and safest way to find
treatments that work. Ideas for clinical trials usually come from
researchers. New therapies are tested on people only after laboratory
and animal studies show promising results. New treatments must prove
to be safe and effective in scientific studies with a certain number
of patients before they can be made widely available.

Risks and
Benefits

There are both
benefits and risks associated with clinical trials.
By
participating in a clinical trial, you can:

  • Take an active
    role in your own health care.
  • Gain access
    to new treatments that are not available to the public.
  • Obtain expert
    medical care at leading health care facilities during the trial.
  • Help others
    by contributing to medical research.

However, clinical
trials also have risks such as

side effects or adverse reactions to medications or treatments.

Anyone interested
in participating in a clinical trial should
should:

– learn as
much as possible about clinical trials in general

  • Understanding
    Clinical Trials,
    provided by ClinicalTrials.gov, a service
    of the National Institutes of Health, for a comprehensive overview
    of clinical trials and questions to ask before participating.

  • Visit the
    National
    Cancer Institute
    for English and Spanish publications on cancer
    clinical trials including What Are Clinical Trials All About?
    A Guide for Patients With Cancer.

– learn more about clinical trials of particular interest to
you

  • ClinicalTrials.gov
    provides patients, family members, health care professionals,
    and members of the public easy access to information on clinical
    trials for a wide range of diseases and conditions. This site
    currently contains over 4,000 clinical studies sponsored primarily
    by the National Institutes of Health. During the coming year,
    additional studies from other Federal agencies and the pharmaceutical
    industry will be included. Learn more about clinical studies on
    health issues of importance to you by searching ClinicalTrials.gov
    for current research.

RESEARCH
ALERTS

  • The Study
    of Tamoxifen and Raloxifene (STAR)
    , one of the largest breast
    cancer prevention studies ever, is now recruiting volunteers at
    more than 400 centers across the United States, Puerto Rico, and
    Canada. The trial will include 22,000 postmenopausal women at
    increased risk of breast cancer to determine whether the osteoporosis
    prevention drug raloxifene (Evista®) is as effective in reducing
    the chance of developing breast cancer as tamoxifen (Nolvadex®
    ) has proven to be. STAR is a study of the National Surgical Adjuvant
    Breast and Bowel Project (NSAPB), a network of professional, and
    is supported by the National Cancer Institute (NCI). For more
    information on STAR and a list of participating centers, visit
    NSABP’s website or call
    the National Cancer Institute’s Cancer Information Service at
    1-800-332-8615 for information in English and Spanish.

  • A Prostate Cancer Genetics Project at the University
    of Michigan has been established to determine possible genetic
    causes of prostate cancer by studying families in which two or
    more living individuals have been affected with prostate cancer.
    Those interested in participating must fit the above criteria,
    will have their health history reviewed, and may be asked to notify
    other members of their family who have/had prostate cancer and
    seek their consent for the study’s team to contact them. Participation
    in the study may also include all of the following:

      • Signing a consent form that outlines the responsibilities
        of participation.
      • Providing information on your family history, including
        members of your family diagnosed with prostate and other
        forms of cancer.
      • Releasing medical record information relating to your
        cancer diagnosis and giving permission to study your tumor
        in the laboratory.
      • Providing a small blood sample.

    Study participants will not be required to travel to Ann Arbor,
    Michigan or pay for any expenses associated with this study.
    If your family has two or more living individuals who have been
    affected with prostate cancer, and you are interested in participating
    in this study contact Kristin Brierley, Research Assistant,
    or Kathleen A. Cooney, M.D. at (734) 647-3014 or (800) 723-9170,
    or by email.